Mild NSFW warning: this post mentions sexual side effects of medication.

SSRIs are the most common type of antidepressant (examples are Prozac/fluoxetine, Zoloft/sertraline, Paxil/paroxetine).

If you have experience with them, do you think they’re a good idea?

I came across a paper about side effects which I haven’t heard discussed before. Many people know that SSRIs have sexual effects, but apparently they also affect fertility.

This paper describes SSRIs as “gonadotoxic”, leading to effects like “decreased sperm concentration and motility, increased [DNA] fragmentation, and decreased reproductive organ weights”.

The paper does say “this effect does seem to be reversible”, so if you stop SSRIs, your sex organs should apparently go back to normal. But still, some people are on SSRIs for long periods of time, right?

I would be interested to hear others’ thoughts, if you have any.

Edit: Thanks for the replies to this post, they’re interesting.

  • shneancy@lemmy.world
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    9 days ago

    though it only coincidentally related SSRIs fucked me up in a different way (which still affected my libido tbf). i didn’t even get to a month of treatment before i decided to quit - they were supposed to help with my anxiety, but instead of helping they made it significantly worse, to the point where i felt as if i was spending my time edging a panic attack at all times of the day. At first i thought i was just getting worse normally, but then i noticed i felt better in the evenings (i was taking them in the mornings). i just couldn’t keep going it was awful

    there’s plenty of people for whom SSRIs are life changers, but sadly i’m not in that group

      • shneancy@lemmy.world
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        9 days ago

        nah it was just general light anxiety, and strong situational anxiety. both stemming semi-directly from adhd